Found: The dial in the brain that controls the immune system

{
  "by": "andreareina",
  "descendants": 4,
  "id": 40243417,
  "kids": [
    40243718,
    40244904,
    40245202
  ],
  "score": 45,
  "time": 1714703500,
  "title": "Found: The dial in the brain that controls the immune system",
  "type": "story",
  "url": "https://www.nature.com/articles/d41586-024-01259-2"
}

{
  "author": "Giorgia Guglielmi",
  "date": "2024-05-01T00:00:00.000Z",
  "description": "Scientists identify the brain cells that regulate inflammation, and pinpoint how they keep tabs on the immune response.",
  "image": "https://media.nature.com/lw1200/magazine-assets/d41586-024-01259-2/d41586-024-01259-2_27034294.jpg",
  "logo": null,
  "publisher": "Nature",
  "title": "Found: the dial in the brain that controls the immune system",
  "url": "https://www.nature.com/articles/d41586-024-01259-2"
}

{
  "url": "https://www.nature.com/articles/d41586-024-01259-2",
  "title": "Found: the dial in the brain that controls the immune system",
  "description": "Scientists have long known that the brain plays a part in the immune system — but how it does so has been a mystery. Now, scientists have identified cells in the brainstem that sense immune cues from the...",
  "links": [
    "https://www.nature.com/articles/d41586-024-01259-2"
  ],
  "image": "https://media.nature.com/lw1200/magazine-assets/d41586-024-01259-2/d41586-024-01259-2_27034294.jpg",
  "content": "<article>\n                <div>\n                        <p>Scientists have long known that <a target=\"_blank\" href=\"https://doi.org/10.1038/d41586-023-00509-z\">the brain plays a part in the immune system</a> — but how it does so has been a mystery. Now, scientists have identified cells in the brainstem that sense <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-021-01396-y\">immune cues from the periphery of the body</a> and act as master regulators of the body’s <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-00871-6\">inflammatory response</a>.</p>\n                        <p><em>doi: https://doi.org/10.1038/d41586-024-01259-2</em></p>\n                    <div><h2 id=\"Bib1\">References</h2></div>\n    <div>\n        <h2>Related Articles</h2>\n        <ul>\n                <li>\n                    <p>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01330-y\">\n                                <img src=\"https://media.springernature.com/lw100/magazine-assets/d41586-024-01330-y/d41586-024-01330-y_17300602.png\" />\n                            Daily briefing: Why exercise is good for us\n                        </a>\n                    </p>\n                </li>\n                <li>\n                    <p>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-022-01502-8\">\n                                <img src=\"https://media.springernature.com/lw100/magazine-assets/d41586-022-01502-8/d41586-022-01502-8_22965224.jpg\" />\n                            Guardians of the brain: how a special immune system protects our grey matter\n                        </a>\n                    </p>\n                </li>\n                <li>\n                    <p>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01636-x\">\n                                <img src=\"https://media.springernature.com/lw100/magazine-assets/d41586-024-01636-x/d41586-024-01636-x_27197946.png\" />\n                            Brain senses immune reactions in the body through the vagus nerve\n                        </a>\n                    </p>\n                </li>\n                <li>\n                    <p>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-025-01655-2\">\n                                <img src=\"https://media.springernature.com/lw100/magazine-assets/d41586-025-01655-2/d41586-025-01655-2_51028546.jpg\" />\n                            How the brain spies on the gut: with help from newfound immune cells\n                        </a>\n                    </p>\n                </li>\n        </ul>\n    </div>\n                        <h2 id=\"subjects\">Subjects</h2>\n                        <ul>\n        <li>\n            <a target=\"_blank\" href=\"https://www.nature.com/subjects/brain\">Brain</a>\n        </li>\n        <li>\n            <a target=\"_blank\" href=\"https://www.nature.com/subjects/immunology\">Immunology</a>\n        </li>\n        <li>\n            <a target=\"_blank\" href=\"https://www.nature.com/subjects/neuroscience\">Neuroscience</a>\n        </li>\n</ul>\n                    <section>\n    <h2 id=\"tablist-heading\">Latest on:</h2>\n    <ul>\n            <li>\n                <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01259-2#latest-content-0-container\">Brain</a>\n            </li>\n            <li>\n                <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01259-2#latest-content-1-container\">Immunology</a>\n            </li>\n            <li>\n                <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-024-01259-2#latest-content-2-container\">Neuroscience</a>\n            </li>\n    </ul>\n        <section>\n            <ul>\n                    <li>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-03265-y\">\n                                <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-03265-y/d41586-026-03265-y_53863134.jpg\" />\n                            <p>Microdosing LSD shows some cognitive benefits — but only for women</p>\n                            <p><span>News</span> <span>19 OCT 26</span></p>\n                        </a>\n                    </li>\n                    <li>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-03303-9\">\n                                <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-03303-9/d41586-026-03303-9_53851616.jpg\" />\n                            <p>Memory stays strong in old age when this brain enzyme is active</p>\n                            <p><span>News</span> <span>16 OCT 26</span></p>\n                        </a>\n                    </li>\n                    <li>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-03252-3\">\n                                <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-03252-3/d41586-026-03252-3_53845766.jpg\" />\n                            <p>Can GLP-1s heal the brain? Obesity drugs get a makeover for addiction and depression</p>\n                            <p><span>News</span> <span>13 OCT 26</span></p>\n                        </a>\n                    </li>\n            </ul>\n        </section>\n        <section>\n            <ul>\n                    <li>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/s41586-026-11176-1\">\n                                <img src=\"https://media.nature.com/w140h79/springer-static/image/art%3A10.1038%2Fs41586-026-11176-1/MediaObjects/41586_2026_11176_Fig1_HTML.png\" />\n                            <p>Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism</p>\n                            <p><span>Article</span> <span>14 OCT 26</span></p>\n                        </a>\n                    </li>\n                    <li>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/s41586-026-11112-3\">\n                                <img src=\"https://media.nature.com/w140h79/springer-static/image/art%3A10.1038%2Fs41586-026-11112-3/MediaObjects/41586_2026_11112_Fig1_HTML.png\" />\n                            <p>Elp1 is required for myeloid differentiation and brain repopulation</p>\n                            <p><span>Article</span> <span>14 OCT 26</span></p>\n                        </a>\n                    </li>\n                    <li>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-02999-z\">\n                                <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-02999-z/d41586-026-02999-z_16124034.jpg\" />\n                            <p>A guide to Nature Index tables</p>\n                            <p><span>Spotlight</span> <span>07 OCT 26</span></p>\n                        </a>\n                    </li>\n            </ul>\n        </section>\n        <section>\n            <ul>\n                    <li>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-03313-7\">\n                                <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-03313-7/d41586-026-03313-7_53840892.jpg\" />\n                            <p>Three reasons why AI is not conscious and perhaps never will be</p>\n                            <p><span>Comment</span> <span>19 OCT 26</span></p>\n                        </a>\n                    </li>\n                    <li>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/d41586-026-03303-9\">\n                                <img src=\"https://images.nature.com/w140h79/magazine-assets/d41586-026-03303-9/d41586-026-03303-9_53851616.jpg\" />\n                            <p>Memory stays strong in old age when this brain enzyme is active</p>\n                            <p><span>News</span> <span>16 OCT 26</span></p>\n                        </a>\n                    </li>\n                    <li>\n                        <a target=\"_blank\" href=\"https://www.nature.com/articles/s41586-026-11174-3\">\n                                <img src=\"https://media.nature.com/w140h79/springer-static/image/art%3A10.1038%2Fs41586-026-11174-3/MediaObjects/41586_2026_11174_Fig1_HTML.png\" />\n                            <p>Targeted stimulation of motor cortex ensembles drives learned movements</p>\n                            <p><span>Article</span> <span>14 OCT 26</span></p>\n                        </a>\n                    </li>\n            </ul>\n        </section>\n</section>\n                        <div>\n        <div>\n            <h2>\n                <img src=\"https://www.nature.com/static/images/logos/nature-careers-logo-3c89275050.svg\" alt=\"Nature Careers\" />\n            </h2>\n        </div>\n        <h3>\n            <a target=\"_blank\" href=\"https://www.nature.com/naturecareers/\">Jobs\n            </a>\n        </h3>\n        <ul>\n                <li>\n                    <div>\n                        <h4><a target=\"_blank\" href=\"https://www.nature.com/naturecareers/job/12865843/deputy-editor-nature-progress-tissue-engineering/?TrackID=62&amp;utm_source=widget&amp;utm_medium=referral&amp;utm_campaign=62\">Deputy Editor, Nature Progress Tissue Engineering</a></h4>\n                        <div>\n                            <p>Job Title: Deputy Editor, Nature Progress Tissue Engineering Location: Shanghai, Beijing, Pune, New Delhi - hybrid working model Closing date: 30th...</p>\n                            <p>Shanghai, Beijing, Pune, New Delhi - hybrid working model</p>\n                            <p>Springer Nature Ltd</p>\n                        </div>\n                    </div>\n                        <p><img src=\"https://www.nature.com/naturecareers/getasset/121465b9-8274-400b-b7a9-ebfcc5a13127/\" />\n                        </p>\n                </li>\n                <li>\n                    <div>\n                        <h4><a target=\"_blank\" href=\"https://www.nature.com/naturecareers/job/12865818/postdoctoral-fellow-position-cancer-immunotherapies/?TrackID=62&amp;utm_source=widget&amp;utm_medium=referral&amp;utm_campaign=62\">Postdoctoral Fellow Position – Cancer Immunotherapies</a></h4>\n                        <div>\n                            <p>Postdoctoral Fellow Position to study Cancer Immunology &amp; design novel Cancer Immunotherapies @ University of Maryland School of Medicine, Baltimore.</p>\n                            <p>21201, Baltimore</p>\n                            <p>University of Maryland School of Medicine, Baltimore</p>\n                        </div>\n                    </div>\n                        <p><img src=\"https://www.nature.com/naturecareers/getasset/387c5b08-c8a0-4d08-abe0-ae3990b7f300/\" />\n                        </p>\n                </li>\n                <li>\n                        <p><img src=\"https://www.nature.com/naturecareers/getasset/121465b9-8274-400b-b7a9-ebfcc5a13127/\" />\n                        </p>\n                </li>\n                <li>\n                        <p><img src=\"https://www.nature.com/naturecareers/getasset/63b75d46-300e-49e0-9ea0-a35ad2488b47/\" />\n                        </p>\n                </li>\n                <li>\n                        <p><img src=\"https://www.nature.com/naturecareers/getasset/c0f89e7c-133d-4e57-925b-ebb1ee32966a/\" />\n                        </p>\n                </li>\n        </ul>\n                        </div>\n                </div>\n            </article>",
  "author": "Guglielmi, Giorgia",
  "favicon": "https://www.nature.com/oscar-static/images/favicons/nature/favicon.ico",
  "source": "nature.com",
  "published": "2024-05-01",
  "ttr": 63,
  "type": "article"
}